Auflistung nach Schlagwort "Antitumor agents"

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  • Preparation of new alkyne-modified ansamitocins by mutasynthesis 
    Harmrolfs, Kirsten; Mancuso, Lena; Drung, Binia; Sasse, Florenz; Kirschning, Andreas (Frankfurt am Main : Beilstein-Institut zur Förderung der Chemischen Wissenschaften, 2014)
    The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a ...
  • Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations 
    Knobloch, Tobias; Draeger, Gerald; Collisi, Wera; Sasse, Florenz; Kirschning, Andreas (Frankfurt am Main : Beilstein-Institut Zur Förderung der Chemischen Wissenschaften, 2012)
    We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants ...